VCF Educational Foundation

Velo-Cardio-Facial Syndrome
Educational Foundation, Inc
Robert J. Shprintzen, Ph.D.
Executive Director

Welcome to the Official Web Site of the Velo-Cardio-Facial Syndrome
(VCFS) Educational Foundation, Inc.  The Foundation is an international not-for-profit,
self-help organization dedicated to providing support and information to
individuals who are affected by Velo-Cardio-Facial syndrome, their families,
physicians and other practitioners. The Foundation is independent of
and not affiliated with — any particular institution.

VCFS — also known as the Shprintzen Syndrome, DiGeorge Sequence and,
regrettably, Catch 22 — is caused by the deletion of a small segment of
the long arm of chromosome 22 (specified as 22q11.2 deletion), and is one
of the most common genetic disorders in humans. Velo-Cardio-Facial
syndrome is characterized by cleft palate, heart abnormalities, learning
disabilities, and over 180 other clinical findings. Please see the VCFS Fact Sheet for details ( requires Adobe Acrobat Reader.)

The VCFS Educational Foundation, Inc. is committed to educating the lay and
professional public by:

  • offering family programs
  • facilitating parent-to-parent
  • distributing educational materials concerning Velo-Cardio-Facial syndrome
  • publishing a periodic information newsletter
  • hosting an annual conference for laymen and professionals

Please choose from our menu (left column) for more information regarding velo-cardio-facial syndrome, including membership in the Foundation. If you have further questions, please contact The Foundation via telephone at (315) 464-6590; via fax at (315) 464-6593, or via email at [email protected].   If you choose, you may also contact the Executive Director, Dr. Robert J. Shprintzen, directly via email at: [email protected].